{"id":33049,"date":"2026-06-29T13:59:58","date_gmt":"2026-06-29T11:59:58","guid":{"rendered":"https:\/\/carpem.fr\/?p=33049"},"modified":"2026-06-29T13:59:58","modified_gmt":"2026-06-29T11:59:58","slug":"pronostic-cancer-endometre","status":"publish","type":"post","link":"https:\/\/carpem.fr\/en\/pronostic-cancer-endometre\/","title":{"rendered":"How can we better predict the progression of endometrial cancer?"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text css=&#8221;&#8221;]<\/p>\n<p class=\"p1\"><b>As part of Green June, the awareness month dedicated to gynecological cancers, we are pleased to present a new video in our series \u201cCARPEM Advances in 5 Minutes\u201d, highlighting recent advances in endometrial cancer research.<\/b><\/p>\n<p class=\"p2\">This video retraces several years of research led by <span class=\"s1\"><b>Guillaume Beinse<\/b><\/span> within <span class=\"s1\"><b>Prof. Pierre Laurent-Puig\u2019s team<\/b><\/span>, through four scientific publications sharing a common goal: <span class=\"s1\"><b>delivering the right treatment to the right patient at the right time.<\/b><\/span><\/p>\n<p class=\"p2\">Discover how two innovative approaches could transform the management of endometrial cancer:<\/p>\n<p class=\"p2\">\ud83e\uddec <span class=\"s1\"><b>A 38-gene RNA signature<\/b><\/span>, designed to refine prognostic assessment and more accurately identify patients at risk of recurrence.<\/p>\n<p class=\"p2\">\ud83e\ude78 <span class=\"s1\"><b>Liquid biopsy<\/b><\/span>, which detects circulating tumor DNA (ctDNA) from a simple blood sample to monitor treatment response and anticipate disease recurrence.<\/p>\n<p class=\"p2\">These studies illustrate the ambition of <span class=\"s1\"><b>translational research<\/b><\/span> at <span class=\"s1\"><b>SIRIC CARPEM<\/b><\/span>: transforming scientific discoveries into practical tools that advance precision medicine for the benefit of patients.<\/p>\n<p class=\"p1\"><i>Content generated with NotebookLM AI and reviewed by the CARPEM teams.<\/i><\/p>\n<ul class=\"ytAttributedStringListGroup\" dir=\"ltr\">\n<li><em><span class=\"ytAttributedStringLinkInheritColor\" dir=\"auto\">Beinse G. Development and validation of a RNAseq signature for prognostic stratification in endometrial cancer. Gynecologic Oncology. 2022. <\/span><\/em><\/li>\n<li><em><span class=\"ytAttributedStringLinkInheritColor\" dir=\"auto\">Beinse G. Discovery and validation of a transcriptional signature identifying homologous recombination-deficient breast, endometrial and ovarian cancers. British Journal of Cancer. 2022. <\/span><\/em><\/li>\n<li><em><span class=\"ytAttributedStringLinkInheritColor\" dir=\"auto\">Beinse G. Highly Specific Droplet-Digital PCR Detection of Universally Methylated Circulating Tumor DNA in Endometrial Carcinoma. Clinical Chemistry. 2022. <\/span><\/em><\/li>\n<li><em><span class=\"ytAttributedStringLinkInheritColor\" dir=\"auto\">Beinse G. ctDNA for Prognostication and Monitoring in Patients with Metastatic Endometrial Carcinoma Treated with Olaparib. Clinical Cancer Research. 2026.<\/span><\/em><\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column]<div class=\"gem-youtube gem-wrapbox gem-wrapbox-style-no-style rounded-corners gem-wrapbox-position-below\" style=\"width: 100%;\"><div class=\"gem-wrapbox-inner gem-ratio-style\" style=\"padding-top: 56.25%\"><iframe class=\"gem-wrapbox-element img-responsive\" width=\"100%\" height=\"300\" allowfullscreen=\"allowfullscreen\" frameborder=\"0\" scrolling=\"no\" marginheight=\"0\" marginwidth=\"0\" src=\"\/\/www.youtube.com\/embed\/S0zTkMUtWQI?rel=0&amp;wmode=opaque\"><\/iframe><\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text css=&#8221;&#8221;] As part of Green June, the awareness month dedicated&#8230;<\/p>\n","protected":false},"author":3,"featured_media":33053,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[314],"tags":[],"class_list":["post-33049","post","type-post","status-publish","format-standard","has-post-thumbnail","category-videos-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>How can we better predict the progression of endometrial cancer? 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