Essai GB
Program 1: Metabolism, Genetics, Immunity & Environment
This program is coordinated by Pr. Guido Kroemer and Pr. Jessica Zucman-Rossi
Major theme of the program
The present research program will explore epidemiological relationships between major signs of aberrant metabolism (overweight, obesity, vitamin deficiencies, metabolic syndrome, diabetes…) to the incidence, molecular subtype, outcome and therapeutic response of several major cancers, while focusing on mammary carcinoma, colorectal cancer, non-small-cell lung cancer and hepatocellular carcinoma). Such epidemiological links will be hypothesis-generating to investigate the possible cause-effect relationship between metabolic alterations at the whole-body level and cancer development in suitable mouse models and to perform interventional clinical trials (diet + exercise + treatment of obesity-related co-morbidities) on cancer patients
WP1: “Decipher the fundamental role of metabolism in cell transformation, immunosurveillance and therapeutic intervention”

RELEASES
Highly Cited Researchers 2023: 8 CARPEM members selected
November 16, 2023Highly Cited Researchers 2023: 8 CARPEM members selected Each year, Clarivate AnalyticsTM publishes Read more »Liver cancer: using AI to predict response to treatment
November 13, 2023Liver cancer: using AI to predict response to treatments Hepatocellular carcinoma, the most common Read more »Diana Passaro, laureate of an ERC Starting Grant 2023
September 18, 2023Diana Passaro, laureate of an ERC Starting Grant 2023 Congratulations to Diana Passaro, PhD, Read more »Transcriptomic Signatures of MSI-high Metastatic Colorectal Cancer Predict Efficacy of Immune Checkpoint Inhibitors
July 31, 2023Transcriptomic Signatures of MSI-high Metastatic Colorectal Cancer Predict Efficacy of Immune Read more »
INFORMATION
- [Job offer] Medical bioinformatics engineer – R&D project manager for NGS analysis tools in oncology
- Job offer – Project Manager Engineer
ACTUALITÉS
Highly Cited Researchers 2023: 8 CARPEM members selected
November 16, 2023Highly Cited Researchers 2023: 8 CARPEM members selected Each year, Clarivate Lire la suite »Liver cancer: using AI to predict response to treatment
November 13, 2023Liver cancer: using AI to predict response to treatments Hepatocellular Lire la suite »Diana Passaro, laureate of an ERC Starting Grant 2023
September 18, 2023Diana Passaro, laureate of an ERC Starting Grant 2023 Congratulations to Diana Lire la suite »Transcriptomic Signatures of MSI-high Metastatic Colorectal Cancer Predict Efficacy of Immune Checkpoint Inhibitors
July 31, 2023Transcriptomic Signatures of MSI-high Metastatic Colorectal Cancer Predict Lire la suite »
INFORMATIONS
- [Job offer] Medical bioinformatics engineer – R&D project manager for NGS analysis tools in oncology
- Job offer – Project Manager Engineer